New Research: MS as a Disease of Endothelial Dysfunction

February 10, 2016

In a recent paper published in the Journal of Neurological Sciences, researchers looked at serum markers of healthy individuals and compared them to people with MS. What they found were that in people with MS, there are circulating microparticles in the blood that aren’t found in healthy people. These markers (CD31+/CD51+/CD61+/CD54+) are microparticles which are shed from the lining of the damaged endothelium. We see the same markers in cardiovascular disease. These markers are associated with coronary artery disease, hypercoagulation, thrombosis (clotting) and stroke:

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